Protective Effect of Olive Oil and Nigella Seed Oil on some Physiological Parameters in Rabbits Administered D-galactosamine

Abstract

This study was to evaluate some physiological parameters for the protective effect of olive oil and nigella seed oil in rabbits administered D-galactosamine (D-GaIN) (600 mg/kg) a single dose with concentrations of body weight of rabbits on some parameters of blood (84) of the male rabbits weighted (400-550g) and (10) weeks of age were randomly divided into six groups, six rabbits in each group, given all the animals normal food during the experimental period of 1,2 and 3 weeks, explained to the animals at the end of each period of experience and took blood samples to measure (Hb,RBC.s, WBC.s,WBC.d,N, WBC.d,L, WBC.d,M, WBC.d,E) was reached the following conclusions: D-GaIN injection caused gradually increase in Hemoglobin level (Hb) and WBC.s and reached the peak level in three weeks post treatment compared to control group. The joint administration of olive oil with D-GaIN to experimental animals improving of effect D-GaIN on oxidative stress with varying degree, there was gradually decreased in mean value of Hb and WBC.s at three-week compared to D-GaIN group. However, the elevation in the mean value of WBC.d.L, WBC.d.N and WBC.d.E in two weeks compared to control. The treatment with Nigella oil after injecting D-GaIN to experimental animals influencing on hematological parameters with varying degree, treatment with Nigella oil after injecting D-GaIN to experimental animals influencing on hematological parameters with varying degree, there was gradually increase in mean value of Hb and WBC.d.L in two weeks compared to control group. Similarly, the mean value of WBC.d.N, WBC.s (9.30±2.03×103 cell/cu.mm. blood) counts were recorded in one week compared to control and D-GaIN groups.