The Impact of Specific Microorganisms Causing the Abortion of a Random Sample of Pregnant Women in Dhamar City, Yemen
DOI:
https://doi.org/10.59167/131g4523Keywords:
Serological Study, Abortion in Pregnant Women, Dhamar, YemenAbstract
This study aimed to determine the prevalence of Cytomegalovirus (CMV), Rubella, Toxoplasma gondii, and anti-phospholipid (APL) antibodies among women who have experienced abortion in Dhamar City, Yemen. Additionally, the research sought to identify risk factors associated with seropositivity for these infections and to compare these factors between pregnant women residing in urban and rural areas. The cross-sectional study involved 200 pregnant women, aged 15 to 38 years, who had a history of one or more unexplained recurrent abortions. These participants were recruited from various healthcare facilities, including Dhamar Hospital, local dispensaries, the Reproductive Health Center, private clinics, and diagnostic laboratories. Participants were screened for IgM and IgG antibodies against CMV, Rubella, Toxoplasma, and anti-phospholipids using Enzyme-Linked Immunosorbent Assay (ELISA). Demographic, socioeconomic, obstetric, and behavioral data were collected via face-to-face interviews utilizing a pretested questionnaire. The seroprevalence of CMV-specific IgG and IgM among the participants was 92.5% and 7.0%, respectively. Rubella-specific IgG and IgM antibodies were detected in 87.0% and 3.5% of the women, respectively. Furthermore, the prevalence of Toxoplasma gondii IgG and IgM was 62.5% and 8.0%, respectively. Seropositivity for anti-phospholipid IgG and IgM were 10.0% and 20.0%, respectively. In conclusion, the presence of IgM antibodies against Rubella, CMV, and Toxoplasma gondii correlated with recent or primary infections. Conversely, positive IgG results for these pathogens indicated prior exposure or convalescent infection.References
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